The Borgias (2011 TV series) - Season 1, Episode 1 - "The Poisoned Chalice"

The Borgias is a historical-fiction drama television series, created by Neil Jordan; it debuted in 2011 and was canceled in 2013.
The series is set around the turn of the 16th century, and follows the Borgia family, an Italian dynasty of Spanish origin. It stars Jeremy Irons as Pope Alexander VI with François Arnaud as Cesare, Holliday Grainger as Lucrezia, David Oakes as Juan, and Aidan Alexander as Gioffre Borgia. Colm Feore also stars as Cardinal della Rovere.

Episode 1 - "The Poisoned Chalice: After the death of Pope Innocent VIII, Cardinal Rodrigo Borgia, with the help of his sons, bribes and cajoles other cardinals to vote for him in the conclave to elect the new pontiff. He succeeds, and assumes the papal throne as Alexander VI. Two other ambitious cardinals, Orsini and Della Rovere, immediately begin plotting against him. When Orsini hosts a dinner for the pope and the cardinals, Rodrigo's son Cesare catches a servant, Micheletto, in the kitchen preparing to poison the Borgias' wine. Offering the assassin better pay if he works for his family, Cesare has Orsini poisoned instead.